Antiretroviral Clinical Trials – Breaking News

Primary Prophylaxis for Cryptococcosis With Fluconazole in Human Immunodeficiency Virus–Infected Patients With CD4 T-Cell Counts <100 Cells/μL and Receiving Antiretroviral Therapy
Sung K et al.
Clin Infect Dis. 2017 Apr 1;64(7):967-970

20th June 2017, by Pr Pedro Cahn

A prospective observational cohort study was conducted in 302 human immunodeficiency virus–infected patients who had a CD4 T-cell count <100 cells/μL and negative serum cryptococcal antigen initiating antiretroviral therapy in a resource-limited setting. During 2-year follow-up, there were no differences of survival rates and occurrences of newly diagnosed cryptococcosis between patients with and without fluconazole for primary prophylaxis of cryptococcosis.

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